Peer Reviewed & Published Articles

Does hyperbaric oxygen therapy improve wound healing?

(Source Document)

Yes, hyperbaric oxygen therapy (HBOT) can promote the healing of surgical wounds. The therapy enhances wound healing through several mechanisms:

  1. Enhanced Oxygen Supply: HBOT increases the amount of dissolved oxygen in the blood, which is delivered to tissues at a higher rate than under normal conditions. This is particularly beneficial for tissues with compromised blood flow, which is common in surgical wounds.
  2. Collagen Production and Angiogenesis: Oxygen is a critical component for collagen synthesis and the formation of new blood vessels (angiogenesis). Both processes are essential for wound healing, as they help to rebuild the tissue and improve blood supply to the wound site.
  3. Reduced Edema and Inflammation: HBOT reduces swelling and inflammation, which can improve circulation and oxygen delivery to the wound. This is particularly helpful in the early stages of healing when reducing inflammation is crucial.
  4. Antibacterial Effects: The high oxygen levels provided by HBOT can inhibit the growth of anaerobic bacteria and enhance the effectiveness of the immune system. This reduces the risk of infection, which can impede wound healing.
  5. Increased Cellular Activity: Oxygen is vital for the energy production of cells, including those involved in wound healing, such as fibroblasts and macrophages. HBOT enhances the function of these cells, promoting more efficient and effective wound repair.
  6. Modulation of Growth Factors: HBOT can influence the release and activity of growth factors and cytokines, which play a significant role in the wound healing process.

Studies have shown that HBOT can be particularly beneficial for certain types of surgical wounds, such as:

  • Chronic non-healing wounds: Including diabetic foot ulcers and venous stasis ulcers.
  • Radiation-induced wounds: Damage caused by radiation therapy, which can impair wound healing.
  • Complicated surgical wounds: Such as those that are infected or have compromised blood supply.

While HBOT is not a standard treatment for all surgical wounds, it can be a valuable adjunct therapy for patients with specific conditions or complications that impair normal wound healing. It is usually administered under the supervision of a specialist and is tailored to the individual patient’s needs.