Peer Reviewed & Published Articles

Does hyperbaric oxygen therapy reduce edema (inflammation)?

(Source Document)

Hyperbaric oxygen therapy (HBOT) is indeed used in the medical field to reduce edema, among other benefits. HBOT involves breathing pure oxygen in a pressurized chamber, which increases the amount of oxygen in the blood and tissues. This has several therapeutic effects, including the reduction of edema. Here’s how HBOT helps in reducing edema:

  1. Increased Oxygen Delivery: HBOT increases the amount of dissolved oxygen in the blood plasma, allowing oxygen to reach areas with reduced or compromised blood flow. This enhanced oxygen delivery helps repair damaged tissues and reduce inflammation.
  2. Vasoconstriction: The high pressure of oxygen in HBOT induces vasoconstriction, which can reduce blood flow to the area of injury and subsequently reduce the leakage of fluid from blood vessels, thereby decreasing edema.
  3. Anti-inflammatory Effects: HBOT has been shown to reduce the levels of inflammatory cytokines and to promote the action of anti-inflammatory cytokines, leading to a decrease in inflammation and swelling.
  4. Angiogenesis and Collagen Synthesis: HBOT promotes the formation of new blood vessels (angiogenesis) and the production of collagen, both of which can aid in tissue repair and reduce the likelihood of fluid accumulation.
  5. Improved Immune Function: HBOT enhances the ability of white blood cells to fight infection and reduce inflammation, contributing to decreased edema.

Research supports the use of HBOT in reducing edema associated with various conditions, such as traumatic injuries, burns, crush injuries, and certain chronic wounds. However, the specific protocol for HBOT, including the pressure level and duration of treatment, can vary depending on the condition being treated and the individual patient’s response.